BDBM518558 (R)-1-((7-cyano-2-(3′-(3-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-6-methyl-1,7-naphthyridin-8-ylamino)-2,2′-dimethylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid::US11124511, Example 33

SMILES Cc1cc2cc(CN3CC[C@@H](O)C3)cnc2c(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)n1

InChI Key InChIKey=ABIMOFDDUILTQA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518558   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Human)
Incyte

US Patent

LigandBDBM518558(US11124511, Example 33 | (R)-1-((7-cyano-2-(3̸...)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2022
Entry Details
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