BDBM518545 (R)-1-((7-cyano-2-(3′-(7-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-2-(trifluoromethyl)pyrido[3,2-d]pyrimidin-4-ylamino)-2,2′-dimethylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)-3-methylpyrrolidine-3-carboxylic acid::US11124511, Example 21

SMILES Cc1c(Nc2nc(nc3cc(CN4CC[C@@H](O)C4)cnc23)C(F)(F)F)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=POKUBRPIWKCYMV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518545   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Human)
Incyte

US Patent

LigandBDBM518545(US11124511, Example 21 | (R)-1-((7-cyano-2-(3̸...)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2022
Entry Details
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