BDBM518455 US11124509, Compound 24

SMILES Cn1ccc(n1)-c1nc(CNc2cccc(F)c2)[nH]c1-c1ccc2ncccc2c1

InChI Key InChIKey=GVXJYDPTNITADU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518455   

TargetTGF-beta receptor type-1(Human)
Clavius Pharmaceuticals

US Patent
LigandPNGBDBM518455(US11124509, Compound 24)
Affinity DataIC50: 200nMAssay Description:Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent