BDBM518409 US11124500, Example 3::[(2R)-1-[4-[1-(Azetidin-3-yl)pyrazol-4-yl]-6-(trifluoromethyl)pyrimidin-2-yl]azetidin-2-yl]methanol
SMILES OC[C@H]1CCN1c1nc(cc(n1)C(F)(F)F)-c1cnn(c1)C1CNC1
InChI Key InChIKey=LVUCTISISVRTJU-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 518409
Affinity DataIC50: 41.9nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Affinity DataIC50: 45.4nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human KHK-C preincubated for 15 mins followed by substrate addition and measured after 20 mins in presence of ATP by Rapidfire MS analy...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human KHK-A preincubated for 15 mins followed by substrate addition and measured after 20 mins in presence of ATP by Rapidfire MS analy...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of KHK in human HepG2 cells incubated for 3 hrs by Rapidfire MS analysisMore data for this Ligand-Target Pair