BDBM518261 7-Fluoro-5-methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-yl)-3,4-dihydro-1H-isoquinoline::US11124495, Example 6

SMILES COc1cc(F)cc2CN(CCc12)c1cnc(nc1)-c1ncccn1

InChI Key InChIKey=JFAJXSWEOCEPTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518261   

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandPNGBDBM518261(7-Fluoro-5-methoxy-2-(2-pyrimidin-2-ylpyrimidin-5-...)
Affinity DataIC50: 454nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent