BDBM518256 US11111270, Compound 4

SMILES CNC(C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)Nc1ccc(OC)cc1

InChI Key InChIKey=NBMUDTIUNPDSAM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518256   

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM518256(US11111270, Compound 4)
Affinity DataKi:  3.75E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM518256(US11111270, Compound 4)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
Go to US Patent