BDBM518247 US11111247, Example 66

SMILES CN1C[C@@H]2CC[C@@H](N2c2ncc3[nH]nc(-c4cnn(c4)C4CC4)c3n2)C1=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 518247   

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM518247(US11111247, Example 66)
Affinity DataIC50: 100nMAssay Description:Phosphorylated (P): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM518247(US11111247, Example 66)
Affinity DataIC50: 100nMAssay Description:un-Phosphorylated (UP): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM518247(US11111247, Example 66)
Affinity DataIC50: 100nMAssay Description:un-Phosphorylated (UP): The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent