BDBM518195 US11111247, Example 25

SMILES CCN1CCN(CC1)c1ccc(cc1C)-c1n[nH]c2cnc(nc12)N1[C@@H](C)CN(C[C@H]1C)C(=O)OC

InChI Key InChIKey=UNHMWPXLLDGEQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518195   

TargetActivin receptor type-1 [147-509](Human)
Incyte

US Patent
LigandPNGBDBM518195(US11111247, Example 25)
Affinity DataIC50: 100nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetActivin receptor type-1 [147-509](Human)
Incyte

US Patent
LigandPNGBDBM518195(US11111247, Example 25)
Affinity DataIC50: 100nMAssay Description:ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent