BDBM517600 N-(6-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-3-(4-(2,2,2-trifluoro-1-hydroxyethyl)-1H-imidazol-1-yl)benzamide::USRE48711, Example 208

SMILES OC(c1cn(cn1)-c1cccc(c1)C(=O)Nc1cccc(n1)-c1nncn1C1CC1)C(F)(F)F

InChI Key InChIKey=HHNJQIRNAMVSNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517600   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gilead Sciences

US Patent
LigandPNGBDBM517600(USRE48711, Example 208 | N-(6-(4-cyclopropyl-4H-1,...)
Affinity DataIC50: 5nMAssay Description:The ability of compounds to inhibit ASK1 kinase activity was determined using a time resolved fluorescence resonance energy transfer [TR-FRET] assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent