BDBM517441 N-(3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl)-4-(2,4-dimethoxypyrimidin-5-yl)picolinamide::USRE48711, Example 49

SMILES COc1ncc(-c2ccnc(c2)C(=O)Nc2cccc(c2)-c2nncn2C2CC2)c(OC)n1

InChI Key InChIKey=VDSUJHZINKZQFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517441   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gilead Sciences

US Patent
LigandPNGBDBM517441(USRE48711, Example 49 | N-(3-(4-cyclopropyl-4H-1,2...)
Affinity DataIC50: 8nMAssay Description:The ability of compounds to inhibit ASK1 kinase activity was determined using a time resolved fluorescence resonance energy transfer [TR-FRET] assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent