BDBM517390 3-(2-chlroophenyl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen-3- yl)-1-(5-methylpyridin-2-yl)- 1H-indazole-6-carboxamide (racemic)::US11104690, Example 185

SMILES Cc1ccc(nc1)-n1nc(-c2ccccc2Cl)c2ccc(cc12)C(=O)NC1(C)CCS(=O)(=O)C1

InChI Key InChIKey=NRTFUSLUGWNMNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517390   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517390(US11104690, Example 185 | 3-(2-chlroophenyl)-N-(3-...)
Affinity DataIC50: 9.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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