BDBM517367 1-(4-fluorophenyl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen- 3-yl)-3-[3-(5-methyl-1,3,4- oxadiazol-2-yl)phenyl]-1H- indazole-6-carboxamide (racemic)::US11104690, Example 164

SMILES Cc1nnc(o1)-c1cccc(c1)-c1nn(-c2ccc(F)cc2)c2cc(ccc12)C(=O)NC1(C)CCS(=O)(=O)C1

InChI Key InChIKey=ALSYRVXWMKUHBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517367   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517367(US11104690, Example 164 | 1-(4-fluorophenyl)-N-(3-...)
Affinity DataIC50: 28nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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