BDBM517336 1-(4-fluorophenyl)-3-(2- fluoropyridin-3-yl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen- 3-yl)-1H-indazole-6- carboxamide (enantiomer A)::US11104690, Example 154-A

SMILES C[C@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1cccnc1F

InChI Key InChIKey=OMOSZDKXYCJSQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517336   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517336(US11104690, Example 154-A | 1-(4-fluorophenyl)-3-(...)
Affinity DataIC50: 17nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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