BDBM517329 1-(4-fluorophenyl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen- 3-yl)-3-[3-(2,2,2- trifluoroethoxy)phenyl]-1H- indazole-6-carboxamide (enantiomer A)::US11104690, Example 147-A

SMILES C[C@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1cccc(OCC(F)(F)F)c1

InChI Key InChIKey=LQSNPFYFXAWOOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517329   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517329(US11104690, Example 147-A | 1-(4-fluorophenyl)-N-(...)
Affinity DataIC50: 5.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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