BDBM517320 3-(5-chloro-2- methoxypyridin-4-yl)-N- (1,1- dioxidotetrahydrothiophen- 3-yl)-1-(4-fluorophenyl)- 1H-indazole-6-carboxamide (enantiomer A)::US11104690, Example 137-A

SMILES OCc1cc(-c2nn(-c3ccc(F)cc3)c3cc(ccc23)C(=O)N[C@@H]2CCS(=O)(=O)C2)c(Cl)cn1

InChI Key InChIKey=PUIBIEUMPBJXMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517320   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517320(US11104690, Example 137-A | 3-(5-chloro-2- methoxy...)
Affinity DataIC50: 5.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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