BDBM517311 US11104690, Example 129-A

SMILES Fc1ccc(cc1)-n1nc(-c2cccc(c2)C#N)c2ccc(cc12)C(=O)N[C@@H]1CCS(=O)(=O)C1

InChI Key InChIKey=OORHHHPGRNGJJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517311   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517311(US11104690, Example 129-A)
Affinity DataIC50: 10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent