BDBM517304 3-(3-cyanophenyl)-1-(4- fluorophenyl)-N-(3-methyl-1,1- dioxidotetrahydrothiophen-3-yl)- 1H-indazole-6-carboxamide (enantiomer B)::US11104690, Example 117-B

SMILES C[C@@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1cccc(c1)C#N

InChI Key InChIKey=MQQVYVFZGBOWEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517304   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517304(US11104690, Example 117-B | 3-(3-cyanophenyl)-1-(4...)
Affinity DataIC50: 6.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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