BDBM517303 3-(2-chloro-5-cyanophenyl)-1-(4- fluorophenyl)-N-[(1S)-1- (hydroxymethyl)-2- methylpropyl]-1H-indazole-6- carboxamide::US11104690, Example 123

SMILES CC(C)[C@@H](CO)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1cc(ccc1Cl)C#N

InChI Key InChIKey=CVJHDHLEPSCDGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517303   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517303(US11104690, Example 123 | 3-(2-chloro-5-cyanopheny...)
Affinity DataIC50: 3.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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