BDBM516935 US11104675, Example 20b

SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(C)n(-c3ccc(Oc4cc[nH]n4)c(Cl)c3Cl)c(=O)c2C)[C@@H]1N

InChI Key InChIKey=TXXNHTSMZGFDPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516935   

LigandPNGBDBM516935(US11104675, Example 20b)
Affinity DataIC50: 5nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent