BDBM516934 US11104675, Example 19b

SMILES CNC(=O)c1ccc(Oc2ccc(c(Cl)c2Cl)-n2c(C)nc(N3CCC4(CO[C@@H](C)[C@H]4N)CC3)c(C)c2=O)cc1

InChI Key InChIKey=QGNASPHDTCYUDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516934   

LigandPNGBDBM516934(US11104675, Example 19b)
Affinity DataIC50: 12nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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