BDBM516911 US11104675, Example 4

SMILES CCC1(N)CCN(CC1)c1cc(=O)n(c(C)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=CAGNEBQFSQCTGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516911   

LigandPNGBDBM516911(US11104675, Example 4)
Affinity DataIC50: 480nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent