BDBM516906 US11104675, Example 2a::US11104675, Example 2b

SMILES C[C@@H]1OC2(C[C@@H]1N)CCN(CC2)c1cc(=O)n(c(C)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=JWPCOLYANHOZLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 516906   

LigandPNGBDBM516906(US11104675, Example 2a | US11104675, Example 2b)
Affinity DataIC50: 7.05E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

LigandPNGBDBM516906(US11104675, Example 2a | US11104675, Example 2b)
Affinity DataIC50: 122nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent