BDBM516882 US11104665, Example 1.3

SMILES CC(=O)N1CCN(CC1)c1ccc(CNc2ccc(OCc3ccnc(c3)C#N)nn2)cc1

InChI Key InChIKey=FEUMJUFMVBNRRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516882   

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM516882(US11104665, Example 1.3)
Affinity DataIC50: 5nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent