BDBM5166 (2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxy-5-methoxyphenyl)eth-1-ene-1-]sulfonyl}-3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enenitrile::Dimeric Tyrphostin 24

SMILES COc1cc(\C=C(/C#N)S(=O)(=O)C(=C\c2cc(O)c(O)c(OC)c2)\C#N)cc(O)c1O

InChI Key InChIKey=RALUAQCUICRVFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5166   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5166((2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxy-5-methoxyph...)
Affinity DataIC50: 940nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed