BDBM516568 US11053243, Example 137::tert-butyl {(1R)-2-[(2S)-2-({2- [4-({[(2S)-1-acetylpyrrolidin-2- yl]carbonyl}amino)phenyl]-3- fluoro-1H-indol-5- yl}carbamoyl)pyrrolidin-1-yl]-2- oxo-1-phenylethyl}carbamate

SMILES CC(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1[nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)cc2c1F

InChI Key InChIKey=WOXPSJXHTJZPDJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516568   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516568(tert-butyl {(1R)-2-[(2S)-2-({2- [4-({[(2S)-1-acety...)
Affinity DataEC50:  0.00900nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent