BDBM516558 US11053243, Example 102::tert-butyl {(1R)-2-[(2S)-2-({2- [4-(1H-imidazol-4-yl)phenyl]- 1H-indol-5-yl}carbamoyl) pyrrolidin-1-yl]-2-oxo-1- phenylethyl}carbamate

SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(cc1)-c1c[nH]cn1)c1ccccc1

InChI Key InChIKey=HFKXFFWXNQJMOS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516558   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516558(US11053243, Example 102 | tert-butyl {(1R)-2-[(2S)...)
Affinity DataEC50:  8.30nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
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Date in BDB:
2/13/2022
Entry Details
US Patent