BDBM516548 N-{2-[4-(acetylamino)phenyl]- 1H-indol-5-yl}-1[(2R)-2-phenyl- 2-(pyrrolidin-1-yl)acetyl]-L- prolinamide::US11053243, Example 58

SMILES CC(=O)Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N3CCCC3)c3ccccc3)ccc2[nH]1

InChI Key InChIKey=DWVOQRHCLCMQAQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516548   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516548(US11053243, Example 58 | N-{2-[4-(acetylamino)phen...)
Affinity DataEC50:  0.970nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent