BDBM516539 N-{2-[4-(acetylamino)phenyl]-1-benzofuran-5-yl}-1-{(2R)-2-[(tert-butoxycarbonyl)amino]-2-phenylacetyl}-L-prolinamide::US11053243, Example 19

SMILES CC(=O)Nc1ccc(cc1)-c1cc2cc(NC(=O)C3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)ccc2o1

InChI Key InChIKey=KVMNLDFNAHDMLE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516539   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516539(US11053243, Example 19 | N-{2-[4-(acetylamino)phen...)
Affinity DataEC50:  25nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent