BDBM516372 US11053241, Compound I-98

SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1F)C(=O)N1CC(F)(F)C1

InChI Key InChIKey=KYIIDSBFMFBABK-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516372   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM516372(US11053241, Compound I-98)
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent