BDBM516287 US11053241, Compound I-13::US11053241, Compound I-16

SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cc(ccn1)-c1ncn(C)n1

InChI Key InChIKey=DJASASUFXZKPQO-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 516287   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM516287(US11053241, Compound I-13 | US11053241, Compound I...)
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM516287(US11053241, Compound I-13 | US11053241, Compound I...)
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent