BDBM516024 US11053241, Compound I-2::US11053241, Compound I-6

SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(c1)-c1ncn(C)n1

InChI Key InChIKey=DGUAOEYRNKPDKI-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 516024   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM516024(US11053241, Compound I-2 | US11053241, Compound I-...)
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM516024(US11053241, Compound I-2 | US11053241, Compound I-...)
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent