BDBM51568 3-(4-fluorophenyl)-7-hydroxy-1-benzopyran-2-one::3-(4-fluorophenyl)-7-hydroxy-2H-chromen-2-one::3-(4-fluorophenyl)-7-hydroxy-coumarin::3-(4-fluorophenyl)-7-hydroxychromen-2-one::3-(4-fluorophenyl)-7-oxidanyl-chromen-2-one::MLS000066060::SMR000079537::cid_5497677

SMILES Oc1ccc2cc(-c3ccc(F)cc3)c(=O)oc2c1

InChI Key InChIKey=XXDAXGKPCUCYLG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 51568   

TargetdTDP-4-dehydrorhamnose 3,5-epimerase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM51568(3-(4-fluorophenyl)-7-hydroxychromen-2-one | 3-(4-f...)
Affinity DataIC50: 1.92E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Michael McNeil, Colorado State Universi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2011
Entry Details
PCBioAssay
TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM51568(3-(4-fluorophenyl)-7-hydroxychromen-2-one | 3-(4-f...)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM51568(3-(4-fluorophenyl)-7-hydroxychromen-2-one | 3-(4-f...)
Affinity DataKi:  1.69E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed