BDBM515647 US11053219, Example 16::US11731956, Example 16

SMILES CNC(=O)c1nnc(cc1Nc1cccc(-c2ncn(C)n2)c1OC)N1CCN(C1=O)C1(C)COC1

InChI Key InChIKey=VWSFAWSDNHJSTD-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515647   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515647(US11053219, Example 16 | US11731956, Example 16)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515647(US11053219, Example 16 | US11731956, Example 16)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent