BDBM515637 BDBM515645::BDBM515733::US11053219, Example 13::US11053219, Example 15::US11053219, Example 21::US11053219, Example 6::US11731956, Example 103

SMILES CNC(=O)c1nnc(cc1Nc1cccc(-c2ncn(C)n2)c1OC)N1CCN(C(C)C)C1=O

InChI Key InChIKey=PJWMIBSFTBGOOJ-UHFFFAOYSA-N

Data  12 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 515637   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Esker Therapeutics

US Patent
LigandPNGBDBM515637(US11053219, Example 15 | US11053219, Example 6 | U...)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent