BDBM515581 US11098063, Example 81

SMILES COc1ccc(F)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(Br)cc1

InChI Key InChIKey=CPJLWFMBUNYSCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515581   

TargetPotassium channel subfamily K member 9(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515581(US11098063, Example 81)
Affinity DataIC50: 21nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetPotassium channel subfamily K member 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515581(US11098063, Example 81)
Affinity DataIC50: 820nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent