BDBM515555 US11098063, Example 53

SMILES Clc1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC(C1)N2C(=O)c1ncoc1C1CC1

InChI Key InChIKey=VBTYXWBNGSZKIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515555   

TargetPotassium channel subfamily K member 9(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515555(US11098063, Example 53)
Affinity DataIC50: 19nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetPotassium channel subfamily K member 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515555(US11098063, Example 53)
Affinity DataIC50: 620nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent