BDBM515527 (7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]methyl}-3-oxa-7,9-diazabicyclo[3.3.1]non-9-yl)(cyclopentyl)methanone::US11098063, Example 17

SMILES Clc1ccc(cc1)-c1nc2ncccn2c1CN1CC2COCC(C1)N2C(=O)C1CCCC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515527   

TargetPotassium channel subfamily K member 9(Human)
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US Patent
LigandPNGBDBM515527(US11098063, Example 17 | (7-{[2-(4-Chlorophenyl)im...)
Affinity DataIC50: 33nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetPotassium channel subfamily K member 3(Human)
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US Patent
LigandPNGBDBM515527(US11098063, Example 17 | (7-{[2-(4-Chlorophenyl)im...)
Affinity DataIC50: 1.20E+3nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent