BDBM515522 US11098063, Example 12

SMILES CC(C)(C)OC(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Br)cc1)C2

InChI Key InChIKey=VPDMXQRQZVDONU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515522   

TargetPotassium channel subfamily K member 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515522(US11098063, Example 12)
Affinity DataIC50: 220nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
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TargetPotassium channel subfamily K member 9(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515522(US11098063, Example 12)
Affinity DataIC50: 13nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
Go to US Patent