BDBM5155 (2E)-2-cyano-N-{10-[(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamido]decyl}-3-(3,4-dihydroxyphenyl)prop-2-enamide::Dimeric Tyrphostin 8

SMILES Oc1ccc(\C=C(/C#N)C(=O)NCCCCCCCCCCNC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)cc1O

InChI Key InChIKey=UXBLTQHRJBAYNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5155   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM5155((2E)-2-cyano-N-{10-[(2E)-2-cyano-3-(3,4-dihydroxyp...)
Affinity DataIC50: 1.30E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed