BDBM515423 US11098061, Compound III-7

SMILES COCCOc1ccc(NC(=O)c2ccc3sc4c(NC[C@@H](C)NC4=O)c3c2)cc1NC(=O)C=C

InChI Key InChIKey=KJUJUFPQDLAJQR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515423   

TargetMAP kinase-activated protein kinase 2(Human)
Celgene Car

US Patent
LigandPNGBDBM515423(US11098061, Compound III-7)
Affinity DataIC50: 100nMAssay Description:Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 2(Human)
Celgene Car

US Patent
LigandPNGBDBM515423(US11098061, Compound III-7)
Affinity DataEC50: >1.00E+3nMAssay Description:Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent