BDBM515139 US11098048, Example 1.14

SMILES O=C(N1C[C@H]2CCN(CC[C@H]2C1)C(=O)c1cc(OCC2CCOCC2)cc(c1)C1CC1)c1ccc2[nH]nnc2c1

InChI Key InChIKey=AASOGRFONRFNKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 515139   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM515139(US11098048, Example 1.14)
Affinity DataIC50: 9nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2), 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent