BDBM514790 US11098041, Example 12

SMILES Cn1cc(cn1)-c1nc2c(ccnc2[nH]1)-c1cnc(CNC(=O)c2noc(n2)C(C)(C)C)c(F)c1

InChI Key InChIKey=ZRHGFCJJGOXTPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514790   

TargetTyrosine-protein kinase BTK(Human)
Merck Patent

US Patent
LigandPNGBDBM514790(US11098041, Example 12)
Affinity DataIC50: 100nMAssay Description:Briefly, 2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent