BDBM514782 US11098041, Example 4

SMILES Cc1c(NC(=O)c2ccc3c(OCC3(C)C)c2)cc(F)cc1-c1ccnc2[nH]c(nc12)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key InChIKey=KFFZSKKUCWKATE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514782   

TargetTyrosine-protein kinase BTK(Human)
Merck Patent

US Patent
LigandPNGBDBM514782(US11098041, Example 4)
Affinity DataIC50: 100nMAssay Description:Briefly, 2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent