BDBM514617 US11098029, Example 52

SMILES COC(=O)N1[C@H](CC#N)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1COC1CC[C@@H](CC1)c1cccc(F)c1

InChI Key InChIKey=BSFUOPJPOSZGMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514617   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514617(US11098029, Example 52)
Affinity DataIC50: 7.80nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent