BDBM514605 US11098029, Example 40::US11098029, Example 41

SMILES CCC1C[C@H](NS(C)(=O)=O)[C@H](CO[C@H]2CC[C@H](CC2)c2ccccc2)N1Cc1ccccc1

InChI Key InChIKey=HPOOHBCVEHBOOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 514605   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514605(US11098029, Example 41 | US11098029, Example 40)
Affinity DataIC50: 4.56nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514605(US11098029, Example 41 | US11098029, Example 40)
Affinity DataIC50: 224nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent