BDBM514599 US11098029, Example 35::US11098029, Example 36

SMILES COC(=O)N1[C@H](C)C[C@@H]([C@@H]1CO[C@H]1CCC(CC1)OCc1ccccc1)N(Cc1ccc(OC)cc1)S(=O)(=O)N(C)C

InChI Key InChIKey=KUZYNVMFJNXXJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 514599   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514599(US11098029, Example 36 | US11098029, Example 35)
Affinity DataIC50: 0.760nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514599(US11098029, Example 36 | US11098029, Example 35)
Affinity DataIC50: 12.5nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent