BDBM514586 US11098029, Example 22

SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@H](CO[C@H]2CC[C@H](CC2)c2cc(F)ccc2F)N1C(=O)OCC(F)F

InChI Key InChIKey=IRSPNEMVGDEBOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514586   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514586(US11098029, Example 22)
Affinity DataIC50: 0.660nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent