BDBM514142 4-(3-((1-(4-chlorophenyl)-2-oxo-2-(6-(pentafluoro-λ6-sulfanyl)indolin-1-yl)ethyl)amino)-5-methoxyphenoxy)butanoic acid ::US11053196, Compound 1

SMILES COc1cc(NC(C(=O)N2CCc3ccc(cc23)S(F)(F)(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1

InChI Key InChIKey=DLDTXHDMKSRPHU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514142   

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514142(US11053196, Compound 1 | 4-(3-((1-(4-chlorophenyl)...)
Affinity DataEC50:  0.640nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
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