BDBM514113 US11052087, Compound 4

SMILES COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(cc1)C#Cc1cnc(nc1)N1CC2CCC(C1)N2C1COC1)[C@H](CN(Cc1c(F)cc(cc1F)-c1ccn(n1)C(F)F)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C(F)(F)F)OC(=O)[C@H](C(C)C)N(C)C)C(C)(C)C(F)(F)F

InChI Key InChIKey=UDJPCCMCLXMIMP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514113   

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandPNGBDBM514113(US11052087, Compound 4)
Affinity DataEC50:  5.71E+3nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
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Date in BDB:
2/6/2022
Entry Details
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