BDBM513935 4-((3-((8-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)oxy)carbonyl)-2,8-diazaspiro[4.5]decan-2- yl)methyl)-5- (trifluoromethyl)phenyl)amino)butanoic acid::US11059822, Example 5::US11691975, Example 5

SMILES OC(=O)CCCNc1cc(CN2CCC3(C2)CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F

InChI Key InChIKey=KKNBRIGYWBUSSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513935   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM513935(4-((3-((8-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)ox...)
Affinity DataIC50: 100nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
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TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM513935(4-((3-((8-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)ox...)
Affinity DataIC50: 5.50E+3nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent